Formerly known as Shy-Drager syndrome, multiple system atrophy with orthostatic hypotension (MSA-OH) is a progressive neurological disorder affecting both the central and autonomic nervous systems. Its primary hallmark is orthostatic hypotension, characterized by a significant drop in blood pressure upon standing. Symptoms commonly associated with MSA-OH include dizziness, general weakness, visual disturbances, swallowing difficulties, sleep disturbances, and reduced sweating. The condition is categorized into three types based on symptomatology: Parkinsonian-type, cerebellar-type, and combined-type.
Treatment
At present, there is no specific cure for multiple system atrophy with orthostatic hypotension (MSA-OH), and treatment focuses primarily on managing symptoms. Medications commonly used include anti-Parkinsonian drugs like Sinemet, which can enhance overall well-being. Blood pressure medications are often prescribed to address orthostatic hypotension, though they may inadvertently elevate blood pressure when lying down. Lifestyle adjustments, such as sleeping with the head of the bed elevated, may also help manage symptoms. In more severe cases involving swallowing or breathing difficulties, artificial feeding or breathing tubes may be necessary. It’s essential to promptly consult a doctor if experiencing symptoms associated with MSA, and a physical therapist can assist in mitigating potential complications.